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The Next Level of Medicine and Nanotechnology

MedNano is an educational site on the evolving field on nanomedicine -- the application of nanotechnology to: the prevention, diagnosis, and treatment of illness and injury; and the enhancement of human health and functioning. As noted by the tagline for a popular monster movie -- "Size Matters."  Ants will likely carry things many times their weight on a relative scale that humans cannot.  However, if ants were our size and we were their scale, then the tables would be reversed.  Nanotechnology takes the strength of tiny engineering and brings it to macro-scale structures.  Objects formed using nanotechnology pieces are not the same as conventionally made goods.  Nanoengineered macro-size things can have greater strength, less weight, greater conductivity, greater heat resistance, and other useful attributes compared to normal macro-size things.

The area of nanotechnology involves the convergence of numerous basic sciences and applied disciplines.  It engages the material sciences of physics, chemistry, substances science and engineering.  It also engages life sciences such as biology, genetics, biomedicine, medicine (including various specialties such as oncology, radiology, and orthopedics) and pharmacology.  Further, it extends into circuitry, computer science, information engineering and data transmission.

Nanotechnology inspires the imagination, but not all visions of the future of nanotechnology are pleasant.  Images of nanotechnology in movies, television, and the popular press sometimes involve reproducing nanobots that have gone awry in an enlarging sea of gray sludge.  However, in real life nanotechnology is much more very possible to keep your clothes free from wrinkles than to take over your city.  Nonetheless, many scientists take these concerns seriously and are working to insure that the fruits of nanotechnology are safe and positive.  For more: GeneFluidics.

Nanotechnology is now being used for numerous commercial applications including: microelectronics, super-conductive circuits, and ultra-fast computers; biomedical investigation, drug delivery systems, and microbe resistant dressings; optics and memory saving instruments; high-strength parts for aerospace and transportation applications; batteries, lighting, and other energy usages; cosmetics, sunscreens, and paints; stain-resistant fabrics, and scratch hindering coverings.  There are no nanotechnology replicators in our residences yet, but there are a lot of simple nano-tech products starting to appear in our catalogs.

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Nanotechnology has moved from abstraction to reality with the development of devices such as the Atomic Force Microscope (AFM), the Scanning Tunneling Microscope (STM), and the Virtual Surface Profiling Microscope (VSPM).  These microscopes do more than just let people observe little products.  They additionally enable placement of material on a dimension of nanometers in a vacuum, liquid or gas.  The AFM has a probe that creates three-dimensional images of unique atoms and molecules at the nano-scale level as it moves across an object’s exterior.  STMs may etch surfaces and propagate particles on scale of nanometers.  Even more more-developed implements for nano-level growth and nanoparticle manufacture are under formation.  Additional Link Virtual.

Nanomachines are electro-mechanical instruments under a hundred nanometers in dimension that have been constructed from atomic-scale parts.  Nanobots are advanced nano-machines that will likely -- sense and adapt to environmental stimuli such as heat, illumination, surfaces, sounds, and chemicals; achieve complex calculations; move, communicate, and coordinate their actions; perform molecular assembly; and, to some extent, repair or copy themselves.

Modern healing tools (such as pacemakers, computerized bionics, implanted joints, endoscopic lasers, and cardiovascular grafts) alter the human body (on a macroscale) that would have been hard for people to imagine a hundred years ago.   In the future, will nanobiotechnology alter the human body (on a nanoscale) in ways that we cannot now imagine?  Are viruses more like little nanomachines than more multi-faceted living organisms and thus best fought by other nano-machines formed by humans?  And Scanning Tunneling Microscope (STM).

If someone from the middle ages were to see an automobile positioning without any creature pulling it, or view images and sounds coming from a television without any visible source, they might think that the automobile and television are themselves “alive.”  We, however, accustomed to engines and electronics, view the automobile and television as inanimate “things” -- intelligently-designed “things,” but “things” notwithstanding.  Nanotechnology will probably lead to the assembly of smart materials that variation shape and function in reaction to ecological conditions and user commands.  If we were to observe a futuristic vehicle that changes configuration to go on land, in the air, or through water, or a robotic arm that reaches up within a patient’s vein to capture a blood clot, how will we view such things?  Would we view them as “alive” (like our middle age counterparts) or would we grow accustomed to nanotechnology objects that variation shape?  Additional Virtual Reality Gaming.

There are numerous uses for nanotechnology in the domain of electronics and computing.  Nanochips can be made by stringing individual atoms together into electronic components or grown using nanocrystalline processes.  For example, one will generally scratch lines in silicon substrate using an Atomic Force Microscope, spread polymer over these lines, apply heat and electricity to assemble wires, and then fabricate them into circuits.   Nanocomputers with elements less than one hundred nanometers in dimension and quantum memory will greatly decrease computing heat and increase computing quickness.

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The capacity of nano-machines to sense action, heat, light, chemicals, and various stimuli in their environment makes them useful for a variety of protection and defense usages.  Their required attributes to deconstruct matter at the nanoscale scale holds promise for detecting and neutralizing chemical and living toxins.  Some environmentalists are concerned that nanobots could go awry and destroy the ecosystem.  While mankind must be vigilant to ensure that this does not occur, there is additionally the possibility that nanorobots could form the ultimate environmentally-friendly recycling system.  Nanobots will potentially one day convert our mountains of trash and poisonous waste into useful commodities and positive composites.  See additionally Nanotechnology.

Nanomedicine is the utilization of nanotechnology to biomedical research and the practice of medicine.  Nanomedical uses currently include: prevention, diagnosis, and healing of illness and injury; and enhancement of human tangible and mental functioning.  For example, nanoparticles that locate and bind to cancer cells will generally be used to image and diagnosis cancer.  When these particles function as nanomedibots that release anti-cancer drugs into the cells or penetrate the cells and deconstruct them mechanically, then they treat cancer.   Particles may also absorb infrared radiation which is converted to heat to ablate target (cancer) tissue. Finally, when administered prophylactically (as a nanovaccination) then they may furthermore help a preventative role.

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Nanopharmacology is the use of nanotechnology to the discovery of innovative atomic entities with pharmacological features.  Nanotechnology is additionally useful for individualized matching of pharmaceuticals to particular people to maximize effectiveness and minimize side effects.  It is also used for  delivery of biological compounds to focused locations or specific types of tissue in the body.  Also see -- CBEN Center for Biological and Environmental Nanotechnology.

Invivo “labs on a chip” employ nanotech biosensors and microfluidics to continuously monitor body temperature, pulse, heart rhythm, blood pressure and flow, oxygenation, or glucose stage; achieve multiple DNA tests; detect pathogens or toxins; or diagnose cancerous tumors while they are very tiny.  External chips can accomplish some of these functions, but regularly not on a continuous basis, especially for those requiring retrieve to tissue within the body.

As nanotechnology and genetics advance, medibots and engineered beneficial microorganisms could be integrated into nanomedibots.  Nanomedibots will be used to diagnosis and treat biomedical conditions that resist diagnosis and healing by present medical research.

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